Logo Virosoft en anglais

A natural and highly effective
integrated pest management tool

  • An essential ally for users of the sexual confusion technique.
  • Only attacks the codling moth and the oriental fruit moth, allowing all other beneficial insects, including pollinating insects, to complete their tasks.
  • Is a reduced risk product for human health and the environment compared to conventional pesticides.
  • Is recognized as a biological insecticide, registered with OMRI in the United States.
  • Contributes to the management of resistance to pesticides and to the reduction of their residues.

About the codling moth and the oriental fruit moth

The codling moth (Cydia pomonella) is part of the Lepidopteran order and the Tortricidae family. It is one of the most widespread pests in orchards of apples, pears and nuts all over the world where it causes considerable losses, especially in apple and pear production.

In the United States, Virosoft CP4 is EPA approved to also fight against the oriental fruit moth or OFM (Grapholita molesta) an insect of the same family as the codling moth. The OFM attacks fruit trees, particularly apple, peach, pear, plum, nectarine or apricot trees, as well as nut trees (for ex: almonds, cashews or walnuts).

The Virosoft CP4 advantage

Virosoft CP4 is the short-and long-term response for protection against the attack of codling moth and OFM. Insects that are still active and found in the major fruit areas of North America. It offers performance that rivals and sometimes surpasses that of conventional chemical insecticides.

Virosoft CP4 makes it possible to carry out a biological fight against the codling moth and the OFM by infecting them with a granulovirus,Cydia pomonella granulosis (CpGV CP-4) which, once ingested, kills the larva even before it can enter the fruit. It thus protects the crops and ensures a better yield.

BioTEPP’s CpGV- CP4 was isolated from codling moths sourced from Canada’s “Microbial Ecozone 4,” which includes the Great Lakes, North-Eastern United States and Canadian Maritimes. It is a different lineage from the other CpGV-M already used in bio-insecticides available on the market.

Approved in Canada and the United States, Virosoft CP4 is recognized for use in organic production and is OMRI (Organic Materials Review Institute) listed.

Virosoft CP4 leaves no residue during late season applications. In addition, it is unlikely to cause adverse effects to birds, bees, invertebrates, fish, mammals and plants because its active ingredient does not penetrate plant tissue.

The Virosoft CP4 infection process

Virosoft CP4 targets newly hatched larvae before they are able to mature into moths. Once the biopesticide is ingested by the larvae, the virus multiplies itself inside de larvae, they die and release more virus particles that are ingested by other larvae.

Once infected, diseased larvae stop feeding and dead infected larvae produce more biopesticides. As a result, the number of codling moth or OFM larvae is reduced within approximately a week. After a period of time, the overall population is considerably reduced as the virus becomes endemic. 

Healthy larvaSick treated larvadead larvaVirus infected exploded larva
healthY larva

Sick treated larva

dead larva
Virus infected exploded larva
Over the years, several clinical trials have been undertaken and have demonstrated Virosoft CP4’s effectiveness. For example, in one of the trials the count of adult moths trapped in control plots after the first and second generations were as high as 270. In plots treated with Virosoft CP4, the count of captured adults was as low as three to 30 after the first generation and only 0.5 to 4.5 after the second generation. This represented more than a 98% reduction in the codling moth population.

Recommended dosage*

One liter (or one quart) of Virosoft CP4 can protect from four to six hectares (10 to 16 acres). It should be used at a dose of 167 ml to 250 ml per hectare (1.6 to 3.2 fluid ounces per acre). For each use, always shake the product well in its container before measuring and pouring into the sprayer.

* Always read the label carefully before use.

When to apply Virosoft CP4

It is important to begin applying Virosoft CP4 as soon as eggs are hatched. In general, this happens between 95-110 DDC (175-200 DDF) after the biofix, i.e. at the first regular capture of codling moths.

Applications should be planned so that the young codling moth larvae can come into contact with the product and ingest it before they get inside the fruit.

How to use Virosoft CP4

Shake the bottle well before filling the sprayer with water. Then add Virosoft CP4 to the sprayer while shaking again vigorously to ensure a uniform dilution of the biopesticide.

Mix in enough water to properly treat the tree canopy while avoiding excessive runoff (up to 1000 liters of solution per hectare or 100 gallons per acre).

Virosoft CP4 can be tank mixed with other products as long as previous use has demonstrated biological compatibility. The pH of the spray tank should be kept almost neutral (smaller than pH8).

In orchards with a high codling moth population, apply Virosoft CP4 at the rate of 250 ml per hectare (3 fluid ounces per acre) every seven days. It should be applied three or four times, at intervals of 7-10 days, for a total of three to four applications per generation of insects.

It is recommended to apply the product late in the afternoon or on a cloudy day to avoid direct exposure to sunlight. Repeat as many times as necessary to maintain control throughout the season.

Consult agricultural service specialists in your area to determine the right time for the first application.

Insect resistance management recommendations

Virosoft CP4 contains CpGV group 31 insecticide.  Although no resistance to Virosoft CP4 has been identified after years of commercial use, some insects may develop a form of resistance to the product.  Appropriate insecticide resistance management strategies must then be followed. 

For example:

  • Where possible, rotate the use of Virosoft CP4 and any other group of similar insecticides containing the CpGV-type virus with different groups that control the same insects.
  • Use tank mixtures with insecticides from a different group if such use is permitted. 
  • The use of insecticides should be part of an integrated pest management program (IPM), including scouting, record-keeping and in consideration of cultural, biological and other chemical control practices.
  • Contact your local specialist or certified crop advisors for any additional recommendations regarding pesticide resistance management and/or IPM recommendations for the specific site and pest problems in your area.
  • For further information or to report suspected resistance, contact us.

How to store Virosoft CP4

Store any unused product in its original container, protected from direct sunlight and out of the reach of children.

For short-term storage and once thawed, it can be stored for up to three months at room temperature (20°C or 68°F) before being opened. Once the container has been opened, it may be stored refrigerated at 4°C or 39°F for up to three months. 

For long-term storage (more than four months between uses), stored frozen at -18°C  or 0.4°F,  the product can be kept for several years without risk of loss of effectiveness.

Where to get Virosoft CP4

Virosoft CP4 can be obtained through the following retailers and/or major agricultural product distributors:

in Canada

Centre Agricole Bienvenue

1115 La Petite Caroline

Rougemont (QC) J0L 1M0

Phone: 450-469-4945

Distribution Husereau

246 rang Ste-Germaine

Oka (Qc) J0N 1E0

Phone: 450-258-4510


Georgian Bay
Orchard Services Inc

416476 10th Line, RR1

Clarksburg (ON) N0H 1J0

Phone: 519-599-6177

Mobile : 519-477-1847

In the United States

G.S. Long Company

2517 Old Town Road

Union Gap (WA) 98903

Phone: 1-800-338-5664

Phone: 509-575-8382

Growmark FS

3150 Stoney Point Road

East Berlin (PA) 17316

Mobile: 717-645-9987


Great Lakes IPM

7563 N Crystal Rd

Vestaburg (MI) 48891

Phone: 989-268-5693


Reister’s Grower Services, LLC

14050 Fruit Ridge Ave

Kent City (MI) 49330

Phone: 616-887-9933

Phone: 616-678-7706, ext. 7708

Labels Canada and United States

Safety Data Sheet

Scientific References

Persistence of a commercial codling moth granulovirus product on apple fruit and foliage.

Baculovirus resistance in codling moth is virus isolate-dependent and the consequence of a mutation in viral gene pe38 

Effect of temperature on long-term storage of codling moth granulovirus formulations

New method for testing solar sensitivity of commercial formulations of the granulovirus of codling moth (Cydia pomonella, Tortricidae: Lepidoptera) 

Biopesticide Demonstration Grant Program (BDGP) Success Story

VirosoftCP4 : premier insecticide viral homologué au Canada pour usage en agriculture

État de situation du carpocapse et du petit carpocapse dans la région

New method for testing solar sensitivity of commercial formulations of the granulovirus of codling moth (Cydia pomonella, Tortricidae: Lepidoptera)

Field evaluation of commercial formulations of the codling moth granulovirus